CLINICAL SIGNIFICANCE OF NATRIURETIC PEPTIDES (review)

Natriuretic peptides are widely known for their protective effects against the development of metabolic syndrome and cardiovascular disease. The important role determining levels natriuretic in diagnosis, assessment severity, prognosis effectiveness treatment heart failure has been proven many studies noted clinical guidelines worldwide. Visceral obesity reduces production action peptides, increasing risk diabetes mellitus 2 type. Metabolic is present 60% patients with chronic failure, most its components contribute to progression include obesity, hypertension, dyslipidemia, insulin resistance, impaired glucose tolerance. prevalence general population 34% constantly due unhealthy diet, sedentary lifestyle stress. rapidly all industrialized countries, affecting 2% adults 10% elderly. Therefore, problem early diagnosis very relevant nowadays. review focuses on pathophysiological relationships between syndrome, approaches correction peptides’ metabolism.